INTRODUCTION
Post-operative polyuria is a well-documented complication of prolonged surgeries. The increased sympathetic drive during surgery leads to stimulation of vasopressin and aldosterone. This stimulation, coupled with the large amounts of intravenous fluid patients receive during surgery, promotes fluid retention1. Decrease in the levels of vasopressin and aldosterone after surgery causes release of retained fluids leading to polyuria. However, polyuria can also be caused by Diabetes Insipidus (DI). While, post-operative Diabetes Insipidus can be transient or permanent depending on the extent of injury to the pituitary gland and is most commonly associated with pituitary surgeries2. Very few cases have been reported after abdominal surgeries. Here we report the case of a 48-year-old woman who developed central DI due to prolonged abdominal surgery with significant intraoperative blood loss.