2.3 Image Preprocessing and Regions of Interest (ROIs) Segmentation
CT images were acquired according to standardized scanning protocols. Preprocessing of the images before ROIs segmentation was performed by a radiologist, and the mean standard deviation of the images was normalized. Lesions of all slices were delineated on the CT images manually by a radiologist who was blinded to the clinical information of the patients, then all contours were reviewed by the other senior radiologist. If the discrepancy was ≥5%, the senior radiologist decided on the tumor borders. Examples of ROIs of CCSK and Wilms’ tumor were shown in Supplementary Fig. 2 .