Introduction
PWCA is an haematologic disorder characterized by agranulocytosis with absence of myeloid precursors in bone marrow with an eritropoiesis and megacariopoiesis preserved. It has been associated with drugs, infectious diseases and autoinmunity1. Thymomas and thymic carcinomas may present autoinmune phenomena fundamentally: miastenia gravis (MG) up to 50% of the cases and pure red cell aplasia (PRCA) up to 5% of the cases 2. However, the incidence of thymoma and PWCA is extremly rare by existing few reports3.
We conducted a search for articles registered in Pub-Med between 1950-2021, which were available in English. The keywords used were: Thymoma, Pure White Cell Aplasia, Agranulocytosis and Granulocytopenia.