Figure 4. NLRP3 determins neuroinflammation of EAE. A, HE staining of mouse brain after induction of EAE in the absence or presence of MCC950 application. B, CD4 staining of mouse brain (n=3 each group). C, LFB staining of mouse brain. D, Expression of MBP of mouse brain (n=3 each group). E, Determination of IL-1β in mouse brain (n=4 each group). F, Determination of TSLP in mouse brain (n=4 each group). Data were presented as mean±SEMin a high-power field (HPF) (*p <0.05, **p <0.01, ***p <0.001)