Figure 3. MOG35-55-indcued neuroinflammation depends on JAK2 signaling. A, HE staining of mouse brain after induction of EAE in the absence or presence of ruxolitinibapplication. B, CD4 staining of mouse brain (n=3 each group). C, LFB staining of mouse brain. D, Expression of NLRP3 and MBP of mouse brain (n=3 each group). E, Determination of IL-1β in mouse brain (n=4 each group). F, Determination of TSLP in mouse brain (n=4 each group). Data were presented as mean±SEMin a high-power field (HPF) (*p <0.05, **p <0.01, ***p <0.001)