Re: Effectiveness of hypertonic saline nebulization in airway clearance
in children with non-cystic fibrosis bronchiectasis: a randomized
control trial
- Rafiaa Valji
, - Rahul Mehta,
- Anne Hicks
Rafiaa Valji
University of Manitoba Max Rady College of Medicine
Corresponding Author:rafiaavalji@gmail.com
Author ProfileRahul Mehta
University of Alberta Faculty of Medicine & Dentistry
Author ProfileAnne Hicks
University of Alberta Faculty of Medicine & Dentistry
Author ProfileAbstract
This first RCT of hypertonic saline use in pediatric non-CF
bronchiectasis patients uses a cross over design and demonstrates an
improvement in predicted FEV1 and FVC. Limitations include lack of
blinding and risk of information bias, as well as reduced precision due
to absence of within subject comparisons.
