Th22 and Th17 cells were associated with clinical parameters in
KD patients
To determine the pathogenic role of Th22 and Th17 cells in the
development of KD, we analyzed the potential association of the levels
of these CD3+CD4+T cell-related
cytokines with the values of clinical parameters in KD patients. We
found that the concentrations of serum IL-22 and IL-17 were correlated
positively with the concentrations of ESR, CRP and NT-proBNP in KD
patients with CAL, respectively (R =0.653, P =0.005;R =0.506, P =0.038; R =0.609, P= 0.009, Fig. 4A;R =0.743, P< 0.001; R =0.837,P< 0.001; R =0.597, P =0.011, Fig. 4B;
respectively). Moreover, KD patients with NCAL also showed the same
trend (R =0.753, P< 0.001; R =0.504,P =0.009; R =0.406, P= 0.039, Fig. 4C; R =0.561,P= 0.003; R =0.444, P= 0.023; R =0.492,P =0.011, Fig. 4D; respectively).