FIGURES LEGENDS
Figure 1. Evolution of CAR-T cells detection in peripheral blood by multiparameter flow cytometry (MFC) and quantitative PCR (qPCR), cytokines measurements and patient clinical management (Case 1). CAR-T cells detection is showed in cells/mL and cytokines in pg/mL. Normal levels: IL-6 0.16-37.7 pg/mL; IL-1 0.17-24pg/mL; IL-15 1.25-13.1pg/mL; GM-CSF 0.5-728.1pg/mL.
G1 CRS: Grade 1 cytokines release syndrome; BMA: Bone marrow aspirate; Dex: Dexamethasone; Cy: Cyclophosphamide.
Figure 2. Evolution of CAR-T cells detection in peripheral blood by multiparameter flow cytometry (MFC) and quantitative PCR (qPCR), cytokines measurements and patient clinical management (Case 2). CAR-T cells detection is showed in cells/mL and cytokines in pg/mL. Normal levels: IL-6 0.16-37.7 pg/mL; IL-1 0.17-24pg/mL; IL-15 1.25-13.1pg/mL; GM-CSF 0.5-728.1pg/mL. G1 CRS: Grade 1 cytokines release syndrome; Dex: Dexamethasone.