List of abbreviations:
ABC transporters: ATP-binding cassettes transporters
ADL: Activity of daily living
CIPN: Chemotherapy induced peripheral neuropathy
CTCAE: Common Terminology Criteria for Adverse Events
EORTC-QLQ-C30: European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire
HFS: Hand–Foot Syndrome
IL: Interleukin
OAT: Organic anion transporters
ROS: Reactive oxygen species
TNF-α: Tumor necrosis factor-alpha
TRPA: Transient receptor potential ankyrin
VAS: Visual analog scale