Consecutive inpatients and medical personnel with suspected COVID-19
were included in a prospective cross-sectional study in a real-life
clinical setting (n=3’658). A positive RT-PCR from a nasopharyngeal swab
was defined as the primary reference standard test representing a
“previous SARS-CoV-2” infection (COVID-19). Abbreviations: ELISA,
enzyme-linked immunosorbent assay; ECLIA, electrochemiluminescence
immunoassay; CLIA, chemiluminescence immunoassay; LFI, lateral flow
immunoassay; N, nucleoprotein; RBD, receptor binding domain of the
SARS-CoV-2 spike glycoprotein; S1/2, domain 1 or 2 of the SARS-CoV-2
spike glycoprotein; RBD+, extended receptor binding domain of the
SARS-CoV-2 spike glycoprotein
Table 3: Diagnostic accuracy of serological immunoassays for the
presence of neutralizing antibodies.