Atypical Ataxia-Telangiectasia with cervical dystonia: A case report

Aceruloplasminemia is an autosomal recessive disease, caused by systemic iron accumulation due to mutations in the Ceruloplasmin gene. We report two Iranian siblings who have diagnosed with aceruloplasminemia. Based on our researches, dementia hasn't been published as the first neurological feature while one of them was presented with pure dementia

After performing DBS surgery on a patient with Tourette syndrome, significant improvement was observed in OCD, but the tic remained unchanged, which contradicts previous studies. Herein we discuss that fluctuations in the therapeutic outcomes may be due to differences in physiological conditions tic- or OCD-specified pathways.