Clinical Implications
In patients with CS, the echocardiographic response following a CRT
upgrade should be carefully evaluated because of the complex etiology
and effect of the corticosteroids. The echocardiographic response to an
upgrade to CRT is not necessarily for predicting the long-term prognosis
in patients with CS. The corticosteroid therapy should be preceded by an
upgrade to CRT in CS patients who have cardiac dysfunction and are
eligible CRT therapy.