3.5∣25-μg DNA patches ameliorated For t 2-induced scratch
behaviors with both therapeutic as well as prophylactic approaches
For midge-allergic patients, the primary goal of treatment is to provide
relief from the annoying itchy allergic reaction to the midge bite. The
For t 2 DNA patches at 25-μg significantly ameliorated midge
allergen-challenge-induced scratch bouts either in mice already
sensitized to the midge (therapeutic) or before being sensitized
(prophylactic) compared with the non-vaccinated groups, resulting in
some instances to numbers of scratch bouts as low as those observed in
the non-sensitized groups (NS), as shown in Fig 2A and 2B, respectively.