3.9∣The therapeutic approach upregulated FOXP3 mRNA expression but not the prophylactic approach
As shown in left panels of Figure 6A and 6B, there was no significant difference in the expression of IL-10 mRNA and protein expression of the splenocytes after rFor t 2 allergen stimulation between NV-T and SV25-T as well as NV-P and SV25-P groups. However, the transcriptional factor of regulatory T cells forkhead box protein P3 (FOXP3) as shown in the right panel of Figure 6A was significantly increased in SV25-T group in comparison with the NV-T group. This change was not observed between the NV-P and SV25-P groups.