3.3∣Patch delivery down-regulated Th2 antibody but up-regulated
Th1 antibody
ELISA was used to determine the effects of the DNA patch vaccine on the
total IgE and For t 2-specific IgG2a levels in the sera. Figure S5A
revealed that the total IgE of SV25 group was significantly decreased.
However, the For t 2-specific IgG2a of SV25 group was significantly
elevated (Figure S5B).