What is the role of post-vaccine antibody quantification tests in eBC patients?
The current evidence supports that seroconversion rates among patients with cancer are similar to those without the disease, particularly in solid tumors like breast cancer 72. Vaccine-wise, serological tests can often be misinterpreted as they might not distinguish between past infection and post-vaccination immunological response 23. Furthermore, serologic testing does not evaluate cellular immune response. When performed against nucleocapsid protein, these tests will not detect immune responses resulting from vaccination, and are not suitable for vaccine decision-making 29. Most experts do not see a clinical application for these tests.