Clinical characteristics
Positive patients by BC and/or ddPCR (n=53) ddPCR-only (+) (n=42) BC & ddPCR (+) (n=11)
P
Age (years) 65.7 ± 13.3 64.7 ± 13.8 69.4 ± 11.2 0.29
Male, n (%) 38 (71.7) 30 (71.4) 8 (72.7) 0.93
Use of vasoactive drugs 35 (66.0) 27 (64.3) 8 (72.7) 0.60
Norepinephrine, n (%) 34 (64.2) 26 (61.9) 8 (72.7) 0.51
Epinephrine, n (%) 6 (11.3) 5 (11.9) 1 (9.10) 0.79
Vasopressin, n (%) 12 (22.6) 8 (19.1) 4 (36.5) 0.22
Mechnical ventilation, n (%) 44 (83.2) 35 (83.3) 9 (81.8) 0.91
Renal replacement therapy, n (%) 14 (26.4) 11 (26.2) 3 (27.3) 0.94
Physical examinations
Temperature (°C)
38.7 ± 0.37
38.8 ± 0.39
38.6 ± 0.21
0.10
Systolic blood pressure (mmHg)
86.4 ±17.6
88.4 ±15.7
78.6 ± 22.8
0.11
Diastolic blood pressure (mmHg)
44.2 ± 9.57
46.4 ± 8.10
41.5 ± 7.88
0.09
Complete blood counts and blood biochemistry
Platelet counts, median (IQR) ×109/L
61.2 (54.4 -93.4)
83.0 (63.5 - 108.5)
40.3 (15.7 - 103.6)
0.12
White blood cell, median (IQR) ×109/L
10.1 (7.72 -13.3)
10.5 (8.19 - 13.3)
8.99 (3.02 - 26.7)
0.77
C reactive protein (mg/L), median (IQR)
152.1 (125.0 - 185.1)
140.6 (110.4-179.1)
204.4 (150.4 -277.8)
0.06
Procalcitonin (pg/L), median (IQR)
4.84 (3.04 - 7.72)
3.70 (2.20 - 6.21)
12.9 (4.13 - 40.4)
0.03
Serum creatinine (μmol/L), median (IQR)
125.6 (107.2 -147.1)
119.2 (98.9 - 143.6)
151.5 (103.9 - 220.9)
0.22
Serum lactate (mmol/L), median (IQR)
3.01 (2.50 - 3.62)
2.76 (2.28 -3.43)
4.26 (2.75 -6.89)
0.04
SOFA score 11.2 ± 4.77 10.5 ± 4.54 13.8 ± 4.85 0.03
APACHE II score 23.2 ± 7.46 21.9 ± 6.63 27.9 ± 8.77 0.02
28 - day mortality, n (%) 34 (64.2) 24 (70.6) 10 (90.1) 0.04