Background: We aimed to determine the relationship between HbA1c levels and the development of postoperative atrial fibrillation (PoAF) . Methods: 288 patients diagnosed with diabet and undergoing on-pump coronary bypass were included in the study. Those with serum HbA1c levels between 5.5-7.0% were defined as Group 1, those with serum HbA1c levels between 7.1-8.9% were defined as group 2, while those with serum HbA1c levels 9.0% and above formed Group 3. Data between groups were compared. The predictive values of the independent variables for the development of PoAF were measured. Results: We did not found difference between groups in terms of development PoAF (p=0.170). Presence of hypertension was determined as an independent predictor for the development of PoAF (p=0.003) but not HbA1c levels (p=0.134). There was 50.5% sensitivity and 61.1% specificity for HbA1c values of 9.06% and above to predict PoAF (AUC: 0.571, p=0.049) Conclusions: HbA1c levels were not an independent predictor of PoAF development. However, we think that high HbA1c levels may be a risk factor for the development of PoAF.

Objective: In this study, it was aimed to compare various parameters during surgery and postoperative cognitive functions in patients undergoing coronary artery bypass graft (CABG) surgery using different levels of perioperative oxygen. Methods: One hundred patients scheduled for elective CABG surgery were included in the study. The patients were divided into two groups according to arterial oxygen levels during surgery. In the normoxia group (NG) (n = 50), PaO2 was between ≥100mmHg and <180mmHg with at least 40% FiO2 mechanical ventilation (MV), and in the hyperoxia group (HG) (n = 50), PaO2 was ≥180 mmHg with 100% FiO2 MV. Hemodynamic parameters, peripheral oxygen saturation (SpO2), cerebral oxygen saturation (rSO2) measured from bilateral sensors, and blood gas values were recorded at the planned measurement times. Mini-mental state examination test (MMSE) was applied to the patients before and at the 12th, 24th hours; on the 1st, 3rd, 6th months after surgery. Results: Extubation time was found to be shorter in NG (p <0.05). Between the groups, rSO2 and mean arterial pressure (MAP) were found to be significantly lower in HG at the time of T4 measurement (p = 0.042, p = 0.038, respectively). MMSE values of the groups at the 1st, 3rd and 6th months were found to be significantly higher in NG (respectively p = 0.017, p = 0.014, p = 0.002). Conclusion: Hyperoxemia application during CABG may be associated with worse postoperative late-term cognitive functions. Keywords: cardiopulmonary bypass; hyperoxia; postoperative complications; cognitive function; spectroscopy, near-infrared.

Background:The aim of the present study was to compare the operative and early postoperative results of the use of del Nido Cardioplegia solution(dNCS) with traditional blood cardioplegia(BC) in adult aortic surgery. Methods: A retrospective single-center study was performed on 118 patients who underwent aortic surgery with cardiopulmonary bypass (CPB) between January 2016 and June 2020. Patients were divided in to two groups according to the type of cardioplegia solution used during the operation. Cardiac arrest was achieved in Group 1(n:65) with traditional BC and in Group 2(n=53) with dNCS. Operative and postoperative outcomes of the patients were compared between the two groups. Results: Patient demographic characteristics were similar between the two groups. dNCS group showed significantly lower aortic cross-clamp (ACC) time(87,5 vs 73,3 min; P=0.001), cardioplegia volume (P<0.001), defibril¬lation(P=0.006), drenaige amount(P=0.026) and inotropic support need (P=0.046).Also dNCS group had significantly lower high sensitive troponin I (hsTnI) values at 6th (P=<0.001) and 24th (P=0.017) hours. Hematocrit levels at hours 6 and 24 were significantly higher in dNCS (P=0.001).Time of intensive care unit stay, duration of extubation and length of hospital stay times were similar in both groups. There was no significant difference in terms of postoperative ejection fraction values(P=0.714). Conclusion: Compared with conventional BC, dNCS provided beter myocardial protection with significantly shorter ACC times, reduced need for intraoperative defibrillation, postoperative lower hsTnI levels and comparable early clinical outcomes for adult patients undergoing aortic surgery. dNCS is a safe and efficient alternative to the traditional BC solution in adult cardiac surgery.