Compliance with ethical standards   
Acknowledgements: Not applicable
Author’s contribution: MX: Concept and designed the study, XX: analyzed data; ZC: Collected the data and helped in data analysis; HX: Drafting of the manuscript
Funding: No Funding was received.
Availability of data and materials: The data used to support the findings of this study are available from the corresponding author upon request.
Ethical approval and consent to participate: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent: It was obtained from all individual participants included in the study.
Consent for publication Not Applicable.
Competing interests: None stated.