Figure 5. An ABC transporter (A) in apo state, T1158, colored from N-terminal (blue) to C-terminal (red); (B) in one of the bound states, T1158v4, colored from N-terminal to C-terminal; and(C) as split into two EUs: D1 (blue): 48-234,347-394,409-615,861-974 and D2 (red): 235-346,692-860,975-1296.
Target T1145 is a starch binding protein Sas627 (Figure 6A). DDomain classifies it into four domains (as numbered in the figure), while DomainParser and SWORD suggest a three-domain arrangement with domains 2 and 4 joined. Starting with the most disjoint 4-domain version and based on the Grishin plot analysis (B) we joined domains 2, 3 and 4 into one EU, while leaving domain 1 separate.