M2 macrophages treatment inhibits the levels of inflammatory cytokines in serum
When compared to the control group, a significant reduction in the expressions of inflammatory cytokines including IL-1β, IL-17A, TNF-α and IL-6 were observed in the M2 macrophages treatment group (p﹤0.05). By contrast, the levels of the anti-inflammatory cytokines IL-4 and IL-10 in M2 macrophages treatment group tended to rise. However, there was no significant difference regarding the expression of IL-4, IL-10 and IL-12 between the control and M2 treatment groups (Figure 2f).