Figure 4. Recognition of SARS-CoV-2 variants of concern (VoC)
A, RBD-specific IgG titers for the group vaccinated with mCuMVTT-RBM measured by ELISA OD450. B, Log OD50 of RBD-specific IgG titer for the group vaccinated with mCuMVTT-RBM (data from A). ELISA plates were coated with either RBDwildtype, RBDK417N, RBDE484K, RBDN501Y, RBDK417N/E484K/N501Y or RBDL452R/E484Q. Statistical analysis (mean ± SEM)One-way ANOVA , n=5 . One representative of 2 similar experiments is shown. The value of p<0.05 was considered statistically significant (*p <0.01, **p <0.001, ***p <0.0001).