Conclusion
Although we cannot exclude the possibility that yet unexplored cycling
protocols could show benefits in the future we believe that the routine
use of the currently tested options in current clinical practice should
not be expected to improve bacterial resistance rates to any appreciable
extent. We hope that this review will inspire a more standardised and
rigorous approach in the future, as with some upgrading, this type of
research could create an enormous contribution to the control of
pathogenic bacteria worldwide.