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Cardiac Iron Overload in Pediatric Oncology and Bone Marrow Transplant Survivors
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  • Sanjay Shah,
  • Leon Su,
  • Kristen Beebe,
  • Erik Ellsworth,
  • Bethany Wisotzkey,
  • M'hamed Temkit,
  • Alexandra Walsh
Sanjay Shah
Phoenix Children's Hospital

Corresponding Author:sshah2@phoenixchildrens.com

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Leon Su
Phoenix Children's Hospital
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Kristen Beebe
Phoenix Children's Hospital
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Erik Ellsworth
Phoenix Children's Hospital
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Bethany Wisotzkey
Phoenix Children's Hospital
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M'hamed Temkit
Phoenix Children's Hospital
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Alexandra Walsh
Phoenix Children's Hospital
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Abstract

Eighteen pediatric oncology or bone marrow transplant (BMT) survivors who had liver iron content of >12 mg/g dry weight also underwent Cardiac MR (CMR) to quantify cardiac iron content. Despite high transfused packed red blood cell volumes (mean 383 ml/kg) patients all had cardiac T2* relaxation times in normal ranges (T2* relaxation time mean 35.1 msec ± 7.1 [normal >20 msec]).