Statistical Analyses
All quantitative results were expressed as mean ± standard error of the
mean (SEM). Collected data were analyzed statistically using SPSS
(version 17) using a one-way ANOVA and the Tukey’s post hoc testing for
subsequent pair-wise comparisons. Data were checked prior to performing
statistical tests for both normality (Shapiro-Wilk) and equal-variance
(Levene’s). Spearman rank correlation analysis was used to determine
potential correlations between metabolites and PHD2 activity.
Significance for all tests was associated with p -values less than
0.05.