Psoriasis is one of the most common chronic cutaneous skin disorders,
having genetic and immunological components. It is currently unknown
what exactly triggers it, or how far reaching are the etiological
factors, although great strides have been made in uncovering the
pathophysiological cascade. Presently, there is a wide diversity of
treatment methods for psoriasis, yet not all are applicable for each
patient. Selection of both drug and dosage depends on both the knowledge
and experience of the treating dermatologist, but also on the specific
characteristics of each patient. Therefore, the treating physicians
should be made aware of the management possibilities, their advantages,
as well as their side effects. Current therapies are divided into
topical, systemic, and biological agents. In the following manuscript,
we present an updated version of these therapies, alongside their
indications, posology and most common side effects, a guide that may be
useful for every practitioner in this field.