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Successful adalimumab graded challenge after delayed reaction to golimumab in a woman with Rheumatoid Arthritis
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  • Federica Rivolta,
  • Andrea Sangalli,
  • Camilla Cappelletti,
  • Alessandra Chiei Gallo,
  • Marco Dubini,
  • Valerio Pravettoni
Federica Rivolta
Policlinico di Milano

Corresponding Author:federica.rivolta@policlinico.mi.it

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Andrea Sangalli
University of Milan
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Camilla Cappelletti
University of Milan
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Alessandra Chiei Gallo
University of Milan
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Marco Dubini
University of Milan
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Valerio Pravettoni
IRCCS Foundation Maggiore Policlinico Hospital
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Abstract

We describe the case of a patient with a diagnosis of rheumatoid arthritis experiencing a mucocutaneous delayed reaction to golimumab. Anyway, there is no consensus regarding the best management of delayed reactions to biologics. Excluding allergic cross-reactivity or sensitization, we finally tested adalimumab by a graded challenge.

Peer review status:ACCEPTED

06 Dec 2022Submitted to Clinical Case Reports
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07 Dec 2022Submission Checks Completed
07 Dec 2022Assigned to Editor
18 Dec 2022Reviewer(s) Assigned
22 Jan 2023Review(s) Completed, Editorial Evaluation Pending
28 Jan 2023Editorial Decision: Revise Major
30 Jan 20231st Revision Received
02 Feb 2023Submission Checks Completed
02 Feb 2023Assigned to Editor
02 Feb 2023Review(s) Completed, Editorial Evaluation Pending
07 Feb 2023Reviewer(s) Assigned
13 Feb 2023Editorial Decision: Accept