REFERENCES
Ai, R., Laragione, T., Hammaker, D., Boyle, D. L., Wildberg, A., Maeshima, K., . . . Firestein, G. S. (2018). Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.Nat Commun, 9 (1), 1921. doi:10.1038/s41467-018-04310-9
Banjanac, M., Munić Kos, V., Nujić, K., Vrančić, M., Belamarić, D., Crnković, S., . . . Eraković Haber, V. (2012). Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells.Pharmacological research, 66 (4), 357-362. doi:10.1016/j.phrs.2012.06.011
Bartok, B., & Firestein, G. S. (2010). Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunological Reviews, 233 (1), 233-255.
Birkenfeld, A., Lee, H., Majumdar, S., Jurczak, M., Camporez, J., Jornayvaz, F., . . . Shulman, G. (2011). Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism. The Journal of biological chemistry, 286 (42), 36163-36170. doi:10.1074/jbc.M111.228817
Carevi, O., & Djoki, S. (1988). Comparative studies on the effects of erythromycin A and azithromycin upon extracellular release of lysosomal enzymes in inflammatory processes. Agents and Actions, 25 (1-2), 124-131.
Cerezo, M., Lehraiki, A., Millet, A., Rouaud, F., Plaisant, M., Jaune, E., . . . Rocchi, S. (2016). Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.Cancer Cell, 30 (1), 183. doi:10.1016/j.ccell.2016.06.007
Colgan, S. (2007). Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2. Int J Biochem Cell Biol, 39 .
Cory, T., Birket, S., Murphy, B., Mattingly, C., Breslow-Deckman, J., & Feola, D. (2013). Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 68 (4), 840-851. doi:10.1093/jac/dks476
Erdi, Sozen, Kartal, N., & Ozer. (2017). Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review. Redox biology .
Galligan, J. J., Fritz, K. S., Backos, D. S., Shearn, C. T., Smathers, R. L., Jiang, H., . . . Petersen, D. R. (2014). Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function. Free Radical Biology & Medicine, 73 , 411-420.
Geng, M., Xu, K., Meng, L., Xu, J., Jiang, C., Guo, Y., . . . Lu, S. (2020). Up-regulated DERL3 in fibroblast-like synoviocytes exacerbates inflammation of rheumatoid arthritis. Clinical immunology (Orlando, Fla.), 220 , 108579. doi:10.1016/j.clim.2020.108579
Goehring, A., Lee, C. H., Wang, K. H., Michel, J. C., Claxton, D. P., Baconguis, I., . . . Gouaux, E. (2014). Screening and large-scale expression of membrane proteins in mammalian cells for structural studies. Nature Protocols, 9 (11), 2574.
Haydar, D., Cory, T. J., Birket, S. E., Murphy, B. S., Pennypacker, K. R., Sinai, A. P., & Feola, D. J. (2019). Azithromycin Polarizes Macrophages to an M2 Phenotype via Inhibition of the STAT1 and NF-κB Signaling Pathways. Journal of immunology (Baltimore, Md. : 1950), 203 (4), 1021-1030. doi:10.4049/jimmunol.1801228
Hetz, C., & Saxena, S. (2017). ER stress and the unfolded protein response in neurodegeneration. Nature Reviews Neurology, 13 (8).
Hu, W. J., Yan, L., Park, D., Jeong, H. O., Chung, H. Y., Yang, J. M., . . . Qian, G. Y. (2012). Kinetic, structural and molecular docking studies on the inhibition of tyrosinase induced by arabinose.International journal of biological macromolecules, 50 (3), 694-700.
Jin, Ye, and, Robert, Rawson, and, . . . and. (2000). ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs. Molecular Cell .
Kabala, P., Angiolilli, C., Yeremenko, N., Grabiec, A., Giovannone, B., Pots, D., . . . Reedquist, K. (2017). Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes. Arthritis Research & Therapy, 19 (1), 207. doi:10.1186/s13075-017-1386-x
Kammoun, H., Chabanon, H., Hainault, I., Luquet, S., Magnan, C., Koike, T., . . . Foufelle, F. (2009). GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. The Journal of clinical investigation, 119 (5), 1201-1215. doi:10.1172/jci37007
Katanasaka, Y., Ishii, T., Asai, T., Naitou, H., Maeda, N., Koizumi, F., . . . Oku, N. (2010). Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78. International Journal of Cancer Journal International Du Cancer, 127 (11), 2685-2698.
Kvien, T., Gaston, J., Bardin, T., Butrimiene, I., Dijkmans, B., Leirisalo-Repo, M., . . . Vischer, T. (2004). Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. Annals of the Rheumatic Diseases, 63 (9), 1113-1119. doi:10.1136/ard.2003.010710
Lhoták, S., Sood, S., Brimble, E., Carlisle, R., Colgan, S., Mazzetti, A., . . . Austin, R. (2012). ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death. American journal of physiology. Renal physiology, 303 (2), F266-278. doi:10.1152/ajprenal.00482.2011
Liu, Y., Pu, Y., Li, D., Zhou, L., & Wan, L. (2017). Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. Life sciences, 170 , 1-8. doi:10.1016/j.lfs.2016.11.024
Lu, Q., Wang, J., Zhang, X., Tian, R., Qiao, L., Ge, L., . . . Wang, L. (2020). TXNDC5 protects synovial fibroblasts of rheumatoid arthritis from the detrimental effects of endoplasmic reticulum stress.Intractable & rare diseases research, 9 (1), 23-29. doi:10.5582/irdr.2019.01139
Mierke, C. (2019). The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells. Reports on progress in physics. Physical Society (Great Britain), 82 (6), 064602. doi:10.1088/1361-6633/ab1628
Nujić, K., Banjanac, M., Munić, V., Polančec, D., & Eraković Haber, V. (2012). Impairment of lysosomal functions by azithromycin and chloroquine contributes to anti-inflammatory phenotype. Cellular immunology, 279 (1), 78-86. doi:10.1016/j.cellimm.2012.09.007
O’Neil, L. J., & Kaplan, M. J. (2019). Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease. Trends Mol Med, 25 (3), 215-227. doi:10.1016/j.molmed.2018.12.008
Ozsvari, B., Nuttall, J., Sotgia, F., & Lisanti, M. (2018). Azithromycin and Roxithromycin define a new family of ”senolytic” drugs that target senescent human fibroblasts. Aging, 10 (11), 3294-3307. doi:10.18632/aging.101633
Parnham, M. J., Haber, V. E., Giamarellos-Bourboulis, E. J., Perletti, G., & Vos, R. (2014). Azithromycin: mechanisms of action and their relevance for clinical applications. Pharmacology & Therapeutics, 143 (2), 225-245.
Pastorino, J. G., & Shulga, N. (2008). Tumor necrosis factor-alpha can provoke cleavage and activation of sterol regulatory element-binding protein in ethanol-exposed cells via a caspase-dependent pathway that is cholesterol insensitive. The Journal of biological chemistry, 283 (37), 25638-25649. doi:10.1074/jbc.M800237200
Porstmann, T., Griffiths, B., Chung, Y., Delpuech, O., Griffiths, J., Downward, J., & Schulze, A. (2005). PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene, 24 (43), 6465-6481. doi:10.1038/sj.onc.1208802
Rahmati, M., Moosavi, M., & McDermott, M. (2018). ER Stress: A Therapeutic Target in Rheumatoid Arthritis? Trends in Pharmacological Sciences, 39 (7), 610-623. doi:10.1016/j.tips.2018.03.010
Reverendo, M., Mendes, A., Argüello, R., Gatti, E., & Pierre, P. (2019). At the crossway of ER-stress and proinflammatory responses.The FEBS journal, 286 (2), 297-310. doi:10.1111/febs.14391
Sawano, A., & Miyawaki, A. (2000). Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis. Nucleic Acids Research, 28 (16), E78. doi:10.1093/nar/28.16.e78
Song, G., Feng, T., Zhao, R., Lu, Q., & Han, J. (2019). CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis. Annals of the Rheumatic Diseases, 78 (12), annrheumdis-2019-215473.
Spagnolo, P., Fabbri, L. M., & Bush, A. (2013). Long-term macrolide treatment for chronic respiratory disease. European Respiratory Journal, 42 (1), 239-251.
Su, L., Zhou, L., Chen, F.-J., Wang, H., Qian, H., Sheng, Y., . . . Li, P. (2019). Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. The EMBO journal, 38 (8), e100156. doi:10.15252/embj.2018100156
van der Veen, M. J., van der Heide, A., Kruize, A. A., & Bijlsma, J. W. (1994). Infection rate and use of antibiotics in patients with rheumatoid arthritis treated with methotrexate. Annals of the Rheumatic Diseases, 53 (4), 224-228. doi:10.1136/ard.53.4.224
Van Schouwenburg, P. A., Rispens, T., & Wolbink, G. J. (2013). Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis.Nature Reviews Rheumatology, 9 (3), 164-172.
Vanaudenaerde, B. M., Wuyts, W. A., Geudens, N., Dupont, L. J., & Verleden, G. M. (2010). Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells.American Journal of Transplantation, 7 (1), 76-82.
Wang, L., Dong, H., Song, G., Zhang, R., Pan, J., & Han, J. (2018). TXNDC5 synergizes with HSC70 to exacerbate the inflammatory phenotype of synovial fibroblasts in rheumatoid arthritis through NF-κB signaling.Cellular & molecular immunology, 15 (7), 685-696. doi:10.1038/cmi.2017.20
Wang, L., Song, G., Zheng, Y., Wang, D., Dong, H., Pan, J., & Chang, X. (2016). miR-573 is a negative regulator in the pathogenesis of rheumatoid arthritis. Cellular & molecular immunology, 13 (6), 839-849. doi:10.1038/cmi.2015.63
Wang, X., Dou, Z., Yuan, Y., Man, S., Wolfs, K., Adams, E., & Van Schepdael, A. (2013). On-line screening of matrix metalloproteinase inhibitors by capillary electrophoresis coupled to ESI mass spectrometry. Journal of Chromatography B Analytical Technologies in the Biomedical & Life ences, 930 , 48-53.
Weijun, W., Ming, Q., Wanwan, J., Zheng, H., Zhongzheng, L., Di, Y., . . . Jianchun, M. (2018). Cystathionine-γ-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis.Cellular & molecular immunology, 16 .
Xu, Yang, Berezowska, Gao, & Peng. (2019). Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma.Cancers, 11 (10), 1502-.
Yeo, L., Lom, H., Juarez, M., Buckley, C., Filer, A., Raza, K., & Scheel-Toellner, D. (2014). A1.53 A novel pro-inflammatory B cell population in the rheumatoid synovium can be identified by expression of FCRL4. Annals of the Rheumatic Diseases, 73 (Suppl 1), A22-.
Yoo, W. H., Sung, M. S., Lee, E. G., Lee, C. H., Lee, M. S., Cheon, Y. H., & Lee, S. I. (2013). AB0138Altered er stress-induced autophagic reactions are associated with increased apoptosis of t lymphocytes in systemic lupus erythematosus. Annals of the Rheumatic Diseases, 72 (Suppl 3), A827-A828.
Zhang, L., Su, Z., Zhang, Z., Lin, J., Li, D., & Pflugfelder, S. (2015). Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease. Jama Ophthalmology, 133 (10), 1117-1123. doi:10.1001/jamaophthalmol.2015.2326
Zuo, E., Cai, Y., Li, K., Wei, Y., Wang, B., Sun, Y., . . . Yang, H. (2017). One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs. Cell research, 27 (7), 933-945. doi:10.1038/cr.2017.81