5. Clinical research
Various clinical trials of
anti-CSC phytomedicines have been carried out to evaluate their safety
and efficacy. In patients with acute myeloid leukemia (AML), Compound
Zhebei Granule combined with chemotherapy was reported to reduce the
percentages of CD34+, CD123+ and CD33+, CD123+ leukemia stem cells(J. Wang et al., 2016) . Further, Table 4. summarizes
the clinical status of phytomedicines targeting CSCs.
Table 4. Clinical status
of phytomedicines targeting CSCs.