TCM: Traditional Chinese Medicine
paclitaxel treatment for ovarian CSCs (Deng et al., 2017) .
Carnosol sensitized glioblastoma CSCs to temozolomide anti-proliferative
effects (Giacomelli et al., 2017) . Phytomedicines not only help
in reducing CSC resistance to treatment; but also show positive results
when given as a combination therapy. A study by Yen et al. depicted that
combinations of Gynura divaricata extract and cisplatin or
doxorubicin or 5-FU show high level of synergism for treating
hepatocellular carcinoma (Yen et al., 2018) .