5. Clinical research
Various clinical trials of anti-CSC phytomedicines have been carried out to evaluate their safety and efficacy. In patients with acute myeloid leukemia (AML), Compound Zhebei Granule combined with chemotherapy was reported to reduce the percentages of CD34+, CD123+ and CD33+, CD123+ leukemia stem cells(J. Wang et al., 2016) . Further, Table 4. summarizes the clinical status of phytomedicines targeting CSCs.
Table 4. Clinical status of phytomedicines targeting CSCs.