TCM: Traditional Chinese Medicine
paclitaxel treatment for ovarian CSCs (Deng et al., 2017) . Carnosol sensitized glioblastoma CSCs to temozolomide anti-proliferative effects (Giacomelli et al., 2017) . Phytomedicines not only help in reducing CSC resistance to treatment; but also show positive results when given as a combination therapy. A study by Yen et al. depicted that combinations of Gynura divaricata extract and cisplatin or doxorubicin or 5-FU show high level of synergism for treating hepatocellular carcinoma (Yen et al., 2018) .