Fig. 7. Effect of mean pore sizes on (a) cell activity and (b) cell toxicity (mean, SEM) within various scaffolds (n=3) 48h after incubation (mean pore sizes: SA=162.5 µm, GOSA0.5=147.4 µm, GOSA1=142.5 µm, RGOSA0.5=116.0 µm and RGOSA1=114.7 µm). There is a strong negative correlation between cellular activity and mean pore size (Spearman R = −0.83) and only a weak positive correlation between cell toxicity and mean pore size (Spearman R = 0.06), that is, the enlargement of mean pore size led to a decrease in cellular activity and did not correlate with cellular toxicity.