Abbreviations
AA, arachidonic acid; ADD, afterdischarge duration; AC, adenylate
cyclase; AEDs, anti-epileptic drugs; AGS, audiogenic seizure; ASP,
Anticonvulsant Screening Program; cGMP, cyclic guanosine monophosphate;
CNS, central nervous system; CREB, cAMP response element-binding; DAG,
diacylglycerol; DBS: deep brain stimulation; DRE, drug-resistant
epilepsy; EL, epilepsy like; ERK, extracellular signal-regulated kinase;
GSK3β, glycogen synthase kinase 3β; HCN, hyperpolarization-activated
cyclic nucleotide-gated; HDC, histidine-decarboxylase; HFS,
high-frequency stimulation; HNMT, histamine N-methyltransferase; H1R,
histamine H1 receptor; H2R, histamine H2 receptor; H3R, histamine H3
receptor; H4R, histamine H4 receptor; IP3, phosphatidyl
inositol-4, 5-biphosphate; KA, Kainic acid; KM, Krushinski-Molodkina;
KO, knock out; LFS, low-frequency stimulation; MAPK, mitogen-activated
protein kinase; MES, maximal electroshock seizure; MTLE, mesial temporal
lobe epilepsy; NINDS/NIH, National Institute of Neurological Disorders
and Stroke/National Institutes of Health; PLA2, phospholipase A2; PKA,
phosphokinase A; PKC, phosphokinase C; PTZ, pentylenetetrazole; RGC,
retrosplenial granular cortex; STR, strychnine; TMN, tuberomammillary
nucleus; VMAT-2, Vesicular monoamine transporter-2; WT, wide type