Abstract The Morrow procedure which uses a median sternotomy with the left ventricle and septum accessed by the aortic valve through a vertical aortotomy is the current standard procedure for left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. However, this approach may be limited in patients who have previously undergone aortic valve replacement. Here, we present a patient who complicated with lymphoma underwent endoscopic septal myectomy to preserve the previously implanted aortic prosthesis. Keywords: Endoscopic surgery, hypertrophic cardiomyopathy, septal myectomy.