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Keywords: Physalin B; Liver fibrosis; GLI1; Acetylation; LAP2α; HDAC1.
Abbreviations: PB, Physalin B; GLI1, glioma-associated oncogene homologue 1; LAP2α, lamina-associated polypeptide 2 α; HDAC1, histone hyperacetylation by histone deacetylase 1;HSCs, hepatic stellate cells; COL1A1, collagen type I α 1 chain; CCl4, carbon tetrachloride; BDL, bile duct ligation; α-SMA, α-smooth muscle actin; Col1A1, collagen type I alpha 1; α‐SMA, α‐smooth muscle actin; TGFβ1, transforming growth factor β1; TIMP-1, TIMP metallopeptidase inhibitor 1; ALT, alanine aminotransferase; AST, asparate aminotransferase; ECM, extracellular matrix.