An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum.

Phool Iqbal; Aamir Shahzad; Zubair Shahid; Aden Iqbal; Muhammad Sohaib Qamar; Firdous Ghori; Halima El Omri; Dina Soliman

doi:10.22541/au.161819718.83894200/v1

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An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum.

Phool Iqbal,
Aamir Shahzad,
Zubair Shahid,
Aden Iqbal,
Muhammad Sohaib Qamar,
Firdous Ghori,
Halima El Omri,
Dina Soliman

Abstract

Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to translocation between chromosomes (9, 22), known as the “Philadelphia chromosome.” In 2016, the World health organization (WHO) introduced a new clinical entity of de novo acute myeloid leukemia (AML). Both diseases share some commonalities, therefore, create a challenge to diagnose.

03 Dec 2020Submitted to Clinical Case Reports

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09 Dec 2020Submission Checks Completed

09 Dec 2020Assigned to Editor

12 Apr 2021Reviewer(s) Assigned

12 Sep 2021Review(s) Completed, Editorial Evaluation Pending

26 Oct 2021Editorial Decision: Revise Minor

07 Mar 20221st Revision Received

08 Mar 2022Submission Checks Completed

08 Mar 2022Assigned to Editor

08 Mar 2022Review(s) Completed, Editorial Evaluation Pending

09 Mar 2022Editorial Decision: Accept

Abstract

Peer review status:ACCEPTED