The Alveolar soft-part sarcoma (ASPS) involving the lung is mostly metastatic, while the primary ASPS involving the lung occurs more rarely. Herein, we reported on another case of primary ASPS, which might be with the earliest onset reported thus far. In this report, surgery was used to excise the lesion as much as possible, and its combination with chemoradiotherapy and anti-angiogenic agent may provide an important reference for the development of standard treatment or first-line treatment for these children patients. This case may provide an important reference for the development of standard treatment or first-line treatment for these children patients.

Primary intratracheal neurilemmoma is rare in children. Here, we reported a case of tracheal neurilemmoma in a 10-year-old girl. She had recurrent cough, dyspnea, and tachypnea. Magnetic resonance imaging revealed a soft-tissue mass was located on the right lateral posterior wall of the trachea. A multidisciplinary operation was performed. Immunohistochemical analysis demonstrated a benign neurilemmoma. Her clinical symptoms and signs improved. We reviewed the clinical features and surgical procedures of ten children with intratracheal neurilemmoma reported in literature. Radiographic techniques and bronchoscopy are helpful for diagnosis of the disease. Long-time follow-up is required.