Horse flies (Tabanidae)
Three salivary allergens have been cloned from the Asian horse flyTabanus yao .94,118 All three allergens,
representing apyrase (Tab y 1), hyaluronidase (Tab y 2), and antigen 5
(Tab y 5), were major allergens in patients with systemic reactions
after horse fly bites. The SI between Tab y 1 and Aedes aegyptiapyrase Aed a 1 is 36%, that of Tab y 2 with vespid and honey bee
hyaluronidases ~40%. Tab y 5 showed only low SI with
Ves v 5 and other wasp antigens 5.