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Anomalous Origin of Left Pulmonary Artery From Ascending Aorta: Embryological Model
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  • Bin Li,
  • Aijun Liu,
  • Ming Yang,
  • Junwu Su
Bin Li
Capital Medical University Affiliated Anzhen Hospital

Corresponding Author:libinazyy@sina.com

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Aijun Liu
Capital Medical University Affiliated Anzhen Hospital
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Ming Yang
Capital Medical University Affiliated Anzhen Hospital
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Junwu Su
Capital Medical University Affiliated Anzhen Hospital
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Abstract

Background Anomalous origin of the left pulmonary artery (ALPA) from the ascending aorta (AA) is a rare congenital heart malformation. Aim To give some of our embryological considerations of ALPA from the AA. Methods We present a patient with ALPA from the AA, right-sided aortic arch, right-sided ductus arteriosus (DA), and aberrant left subclavian artery (LSCA). Results The distal end of ALPA was cut off, the proximal end was sutured, and the distal end was directly anastomosed to the left wall of the main pulmonary artery (MPA). Conclusion The failure of migration and differentiation of cardiac neural crest cells at the fourth and sixth archs result in unilateral arch agenesis or failure of detachment of the left sixth arch from the aortic sac, which form ALPA the AA.