Supplementary Table 3. Initial (i) and final (f) assessments and pairwise comparisons (A X C. B X C and A X B).
Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Initial and final assessments Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons Pairwise comparisons
A X C A X C B X C B X C A X B A X B A X B
A (n = 8) B (n = 6) C (n = 8) p-value (95% CI) p (95% IC) p (95% IC) p (95% CI)
NEUPSILIN
Reverse counting, s, (SD)** i 32 (11.90) 41 (16.38) 30 (10.27) 0.006 (2.2; 11.63) c 0.002 (5.9; 20.55) d 0.104 (-3.0; 25.70) d 0.763 (-16.4; 12.53) d
f 20 (7.11) 31 (7.28) 31 (11.35)
Digit sequence repetition, right answers (SD)* i 2 (0.99) 3 (2.99) 2 (1.39) 0.039 (-1.9; -0.05) c 0.537 (-1.2; 2.20) d 0.765 (-2.6; 3.38) d 0.953 (-3.4; 3.26) d
f 3 (0.35) 4 (1.26) 3 (0.76)
Long-term memory, right answers (SD)* i 2 (1.41) 1 (0.89) 1 (1.25) 0.036 (-1.2; -0.05) c 0.705 (-1.1; 1.64) d 0.197 (-2.2; 0.50) d 0.205 (-2.8; 0.68) d
f 2 (0.64) 2 (0.82) 2 (1.06)
Recognition, right answers (SD)* i 10 (1.28) 8 (2.71) 10 (1.07) 0.008 (-2.6; -0.45) c 0.156 (-4.0; 0.70) d 0.013 (-6.1; -0.88) d 0.113 (-4.3; 0.51) d
f 11 (2.20) 12 (4.03) 10 (1.93)
Visual memory, right answers (SD)* i 2 (0.74) 2 (0.82) 2 (0.99) 0.008 (-0.9; -0.15) c 0.744 (-0.9; 0.68) d 0.732 (-0.9; 1.20) d 0.549 (-0.7; 1.32) d
f 3 (0.00) 3 (0.52) 3 (0.74)
Evocated potentials, ms (SD)
55 dB
N1 /g/ i 102 (8.38) 100 (6.02) 101 (8.23) 0.016 (2.1; 18.59) c 0.091 (-3.1; 37.12) d 0.168 (-7.7; 39.24) d 0.865 (-16.3; 13.92) d
f 85 (5.68) 85 (18.37) 101 (24.63)
IOI-HA
2 0.001 (-2.2; -0.76) d 0.000 (-2.3; -0.96) d 0.765 (-1.0; 0.77) d
3 0.033 (-2.6; -0.13) d 0.158 (-2.6; 0.47) d 0.612 (-1.1; 1.73) d
4 0.021 (-2.0; -0.21) d 0.015 (-2.1; -0.29) d 0.732 (-0.6; 0.44) d
5 0.016 (-2.9; -0.38) d 0.073 (-2.7; 0.14) d 0.350 (-0.4; 1.08) d
7 0.031 (-1.4; -0.08) d 0.076 (-1.4; 0.08) d 0.732 (-0.4; 0.60) d
Total 0.043 (-1.4; -0.02) d 0.030 (-1.3; -0.09) d 0.980 (-0.5; 0.46) d
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Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds. Abbreviations: A, advanced technology; B, basic technology; C, placebo; CI, confidence interval; NEUPSILIN, Brief Neuropsychological Assessment Instrument; dB, decibel; N1, N1 wave; ms, milliseconds; SD, standard deviation; s, seconds.