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Measuring coagulopathy in pediatric craniofacial surgery
  • +4
  • Alexandra Borst,
  • Christopher Bonfield,
  • Poornachanda Deenadayalan,
  • Chi Le,
  • Meng Xu,
  • Jenna Sobey,
  • Srijaya Reddy
Alexandra Borst
Monroe Carell Junior Children's Hospital at Vanderbilt

Corresponding Author:alexandra.borst@vumc.org

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Christopher Bonfield
Monroe Carell Junior Children's Hospital at Vanderbilt
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Poornachanda Deenadayalan
Vanderbilt University
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Chi Le
Vanderbilt University School of Medicine
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Meng Xu
Vanderbilt University School of Medicine
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Jenna Sobey
Monroe Carell Junior Children's Hospital at Vanderbilt
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Srijaya Reddy
Monroe Carell Junior Children's Hospital at Vanderbilt
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Abstract

Complex cranial vault reconstruction (CCVR) for repair of craniosynostosis is a procedure associated with high risk of bleeding and resultant coagulopathy. The goal of this study was to describe lab parameters in a cohort of pediatric patients undergoing CCVR and identify if standard hematologic and coagulation laboratory results could predict blood loss. We found that standard hematologic and coagulation laboratory parameters predicted intraoperative and postoperative blood loss, but provided limited mechanistic information to improve our understanding of coagulopathy in craniofacial surgery. Future laboratory-based studies would be useful in providing a comprehensive model of coagulopathy in this population.