Rhythm control agents
Amiodarone was the most often used anti-arrhythmic agent (49.7%) for rhythm control in the Balkan region, followed by propafenone (24.3%). In the EORP-AF Pilot Registry [25], the PREFER in AF registry [31], the Central Registry of the German Competence NETwork on Atrial Fibrillation (AFNET) [33] and in the EuroHeart survey [30] amiodarone was also most often used antiarrhythmic agent for rhythm control. However, in the BALKAN-AF survey the proportion of patients medicated with amiodarone was the highest when compared to the above mentioned studies where the proportion of patients on amiodarone varies from 13.8% to 35.0%. Similarly to our study, class Ic agents are the second from the most frequently used anti-arrhythmic drugs in other registries [25, 30, 31, 33]. However, the proportion of Ic agents is lower in the above mentioned registries than in our study [25, 30, 31, 33].