Rhythm control agents
Amiodarone was the most often used anti-arrhythmic agent (49.7%) for
rhythm control in the Balkan region, followed by propafenone (24.3%).
In the EORP-AF Pilot Registry [25], the PREFER in AF registry
[31], the Central Registry of the German Competence NETwork on
Atrial Fibrillation (AFNET) [33] and in the EuroHeart survey
[30] amiodarone was also most often used antiarrhythmic agent for
rhythm control. However, in the BALKAN-AF survey the proportion of
patients medicated with amiodarone was the highest when compared to the
above mentioned studies where the proportion of patients on amiodarone
varies from 13.8% to 35.0%. Similarly to our study, class Ic agents
are the second from the most frequently used anti-arrhythmic drugs in
other registries [25, 30, 31, 33]. However, the proportion of Ic
agents is lower in the above mentioned registries than in our study
[25, 30, 31, 33].