11 | TABLE HEADINGS
Table 1: Comparison of the implemented features in each of the four tested software packages, including CRABS, ecoPCR, MetaCurator, and RESCRIPt. Amplicon extraction methodologies implemented in current software: (i) in silico PCR; (ii) LA – Multiple Sequence Alignment; (iii) PGA – Pairwise Global Alignment; and (iv) PHMM – Profile Hidden Markov Models. * indicates the code is not implemented in the software package, but provided as shell scripts in the tutorial workflow.