Study limitations
This study was a single center trial and the study population was relatively small. The LAP was not evaluated continuously because the insertion of the cryoballoon into the long sheath was needed to perform the PVI and an accurate LAP could not be evaluated during cryoballoon ablation. The sedation status was variable even with the same dose of an anesthetic agent, and the collapsibility of the upper airway also changed during the procedure. An additional propofol bolus administration as the patient status dictated easily deepen the sedation status for a certain length of time. Therefore, the efficacy of the ASV for the LAP could be variable and labile.
The present study did not perform polysomnography to evaluate the extent of the OSA before the ablation procedure. Therefore, the prevalence of OSA might have been underestimated. Further prospective studies that enroll larger numbers of patients with OSA and investigate the LAP change after the ASV treatment are expected.