Study population and baseline patient characteristics
Fifty-one consecutive patients underwent the cryoballoon PVI. The mean
age was 65.8 ± 10.4 years old and 41 (80.4 %) patients had a male
gender. The proportion of paroxysmal and non-paroxysmal AF was 27 (53.0
%) and 24 (47.0 %) patients, respectively. Two patients were diagnosed
with obstructive sleep apnea (OSA) and were introduced to continuous
positive airway pressure therapy. The patient characteristics are shown
in Table 1 .
LAP evaluation (Table 2 )
The LAPs were sequentially measured before and after the ASV support in
a total of 51 enrolled patients. The BIS value at the time of the LAP
measurement was similar between that before and after the ASV support
(67.7 ± 13.1 vs. 68.5 ± 12.7, p = 0.26). Out of 27 patients with
paroxysmal AF, the LAP was measured during sinus rhythm in 25 and during
AF in the remaining 2. In all 24 patients with non-paroxysmal AF, the
LAP was measured during AF or atrial flutter. There was no significant
difference in the average LAP between that before and after the ASV
support (10.9 ± 4.8 mmHg vs. 11.6 ± 3.7 mmHg, p = 0.14).