SEVERE/REFRACTORY AUTOIMMUNE HEMOLYTİC ANEIMIA İN AN INFANT SUCCESSFULLY
TREATED WITH RITUXIMAB
Abstract
Autoimmune hemolytic anemia (AIHA) is a rare condition in children which
differs from the adult form. It is defined by immune-mediated
destruction of red blood cells caused by autoantibodies. Treatment
depends on the type of AIHA, its severity and whether there is an
underlying disorder. Rituximab is now the preferred second-line
treatment for primary warm autoimmune hemolytic anemia (Waiha). Here, we
present a 2-monthboy with wAIHA, resistant to steroids and cyclosporin
A, who was successfully treated with rituximab. Our patient is one of
the youngest cases in the literature.