Table 1. Characteristics of included studies.
Study name
Shrestha M et al.10
Monsefi et al.11
Charchyan et al.15
Beckmann et al.13
Hou et al.14
Shah et al.16
Year
2015
2018
2020
2021
2021
2021
Country
Germany
Germany
Russia
Germany
China
USA
Study design
Retrospective comparative
Retrospective comparative
Retrospective PSM
Retrospective observational
Retrospective PSM
Retrospective comparative
Study period
2011-2014
1991-2015
2016-2019
2011-2018
2016-2021
2015-2019
N of patients
26
90
30
62
52
16
Age (yrs)
47.6 ± 13
57 ± 14
44.4 ± 14.5
48.5 ± 12.1
45.9 ± 12.1
51.1 ± 11.9
Marfan syndrome
1 (3.9)
9 (10)
5 (17)
6 (9.7)
5 (9.6)
3 (18.8)
Bicuspid aortic valve
10 (38.5)
16 (18)
3 (10)
24 (38.7)
4 (7.7)
2 (12.5)
CPB time (mins)
175.8 ± 41.9
188 ± 48
147 ± 14
191.4 ± 39
139 ± 30.9
199.5 (182.5 - 208)*
ACC time (mins)
115.6 ± 30.3
138 ± 32
130 ± 17
126.4 ± 28.8
110.6 ± 19.9
168.5 (154.5 – 179)*
Concomitant aortic leaflet repair
11 (42.3)
44 (49)
n/a
30 (48)
n/a
n/a
Re-exploration for bleeding
1 (7.1)
8 (9)
0 (0)
5 (8.1)
0 (0)
1 (6.3)
30-day stroke
0 (0)
1 (1)
1 (3.3)
1 (1.6)
n/a
0 (0)
30-day mortality
0 (0)
0 (0)
1 (3.3)
1 (1.6)
0 (0)
0 (0)
ICU stay (d)
1.3 ± 0.6
1.1 ± 0.5
1.2 ± 0.4
1.8 ± 1.4
2.1 ± 1.3
3 (2 - 3.5)*
Hospital stay (d)
10.4 ± 6.8
9 ± 4
8 ± 2.6
n/a
n/a
6 (6 – 7)*