Study name Year Country Study design Device Type of valve complication n Age (yrs) Possible mechanism Outcome Follow-up
Toggweiler[24] 2008 Switzerland CR Impella 2.5 Functional mitral stenosis 1 70 Device displacement Mitral stenosis resolved, mild regurgitation Until discharge
Chandola[14] 2012 Canada CR Impella 2.5 Aortic valve injury 1 45 Device removal TAVI for AR Until discharge
Elhussein[22] 2014 Canada CR Impella 5.0 Acute MR 1 75 Chordal rupture due to the device displacement MOF; Died N/A
Sharma[17] 2014 USA CR Impella 2.5 AR 1 18 Commissural malcoaptation Medical treatment 6 months
Bhatia[19] 2017 USA CR Impella CP Acute MR 1 52 Chordal rupture due to the device insertion or removal MVR+CABG; Died postoperatively N/A
Hong[15] 2019 USA CR Impella 5.0 Aortic valve injury 1 50 Device upgrade or frequent manipulation AVR for AR and upgrade to CentriMag; Heart and kidney transplant Until discharge
Khalid[20] 2020 USA CR Impella 5.0 Acute severe MR 1 47 Chordal rupture due to the device displacement MVR+CABG Until discharge
Pivato[21] 2020 Italy CR Impella CP Acute severe MR 1 85 Chordal rupture due to the device displacement Mitraclip 1 month
Butala[18] 2020 USA RO Impella Increase in AR 9 64±5.5 Not investigated Not investigated No follow-up
Vila[16] 2020 UK CR Impella CP Aortic valve injury 1 34 Device repositioning AVR Until discharge