Associations with child ADHD symptoms
In the analysis at age 5 years, children of mothers who ever used SSRI/SNRI in pregnancy had a lower small risk of ADHD symptoms compared to non-medicated (weighted β (wβ): -0.23, 95% CI: -0.39, -0.08) or discontinuers (wβ: -0.18, 95% CI: -0.45, 0.09) (Table 2). The negative association between SSRI/SNRI exposure and ADHD symptoms in preschoolers seemed to be driven by duration of exposure, with larger effect size for exposure in 9-20 weeks. There was no difference in ADHD symptoms between groups according to longer exposure duration (Table 2).