fifty years old woman with dyspnea of exertion, rupture of sinus Valsalva to right atrium and patent foramen oval in echocardiography referred to our hospital. After device closure of the rupture, she developed orthostatic hypoxemia. Invasive intra-cardiac evaluation confirmed the diagnosis of Platypnea-Orthodeoxia Syndrome which was closed with device

A fifty years old woman with dyspnea of exertion and rupture of sinus Valsalva to right atrium in echocardiography referred to our hospital. After device closure of the rupture, she developed orthostatic hypoxemia. Invasive intra-cardiac evaluation confirmed the diagnosis of Platypnea-Orthodeoxia Syndrome which was managed by device closure for PFO.