RESULTS
The initial search yielded 2,808 articles; after electronic and manual
deduplication on title review 2,502 studies remained. An abstract review
led to the exclusion of the least relevant articles, with 159 selected
for full-text review. From that we identified 37 studies with 71,455
patients for which quantitative analysis was possible (figure 1) (6-42).
All the studies were observational, and 23 out of 37 included patients
who had undergone TAVR at a single institution (62%). The incidence of
PPMI after TAVR was 22%. The mean age of our study population ranged
between 76–84 years, with 52% female. Logistic EuroSCORE or the
STS-PROM score was used to assess the pre-procedural risk in the
majority of the studies. By contrast, in seven studies the authors
reported no relevant information. Table 1 shows the baseline
characteristics of patients in the included studies.
The type of valve implanted and the access routes used in each study are
summarized in Table 2. In 17 studies SEV was used exclusively and BEV
exclusively in 9; both valve types were used collectively in 11. Of the
studies included in the analysis, the incidence of BEV was 64% compared
to SEV 35.5%, while other valves were 0.5%. Fifty-four different
predictors were eligible for the analysis, and two or more
non-overlapping datasets were available for 25 (supplement table 2).
Results were divided based on demographic, electrocardiographic,
imaging, valvular, and procedural predictors (figure 2).