This results then in a Pareto front representing a set of optimal solutions, each one being a trade-off of the objective functions whereby no other solution can satisfy both objective functions better. Exemplarily for these results, figureĀ 5 shows a multi-objective optimization run to increase the CCI space-time yield while decreasing the cofactor concentration after 50, 200, and 300 generations respectively: as can be seen in figureĀ 5, 200 generations are sufficient as no significant improvement is obtained even when increasing the generation number.