Table 2: Competition binding |
Table 2: Competition binding |
Table 2:
Competition binding |
Table 2: Competition binding |
Table 2:
Competition binding |
Table 2: Competition binding |
Table 2:
Competition binding |
Table 2: Competition binding |
|
|
[125I]-hGLP-2(1-33.M10Y) |
[125I]-hGLP-2(1-33.M10Y) |
[125I]-hGLP-2(1-33.M10Y) |
[125I]-hGLP-2(3-33,M10Y) |
[125I]-hGLP-2(3-33,M10Y) |
[125I]-hGLP-2(3-33,M10Y) |
|
Ligand
|
pEC50
(M) ± SEM
|
EC50
[nM]
|
n
|
pEC50
(M) ± SEM
|
EC50
[nM]
|
n
|
hGLP-2R |
hGLP-2(1-33) |
7.9 ± 0.12 |
14 |
5 |
7.8 ± 0.09 |
15 |
5 |
|
hGLP-2(1-33,M10Y) |
7.2 ± 0.07 |
59 |
5 |
7.1 ± 0.13 |
78 |
6 |
|
hGLP-2(3-33) |
7.2 ± 0.08 |
57 |
5 |
7.1 ± 0.13 |
81 |
6 |
|
hGLP-2(3-33,M10Y) |
7.3 ± 0.10 |
49 |
5 |
7.4 ± 0.13 |
41 |
5 |
mGLP-2R |
hGLP-2(1-33) |
8.2 ± 0.13 |
6.6 |
3 |
7.7 ± 0.16 |
18 |
3 |
rGLP-2R |
hGLP-2(1-33) |
8.3 ± 0.24 |
5.4 |
3 |
8.2 ± 0.18 |
6.5 |
3 |
hGLP-1R |
hGLP-2(1-33) |
6.9 ± 0.50 |
130 |
3 |
6.5 ± 0.5 |
330 |
3 |
mGLP-1R |
hGLP-2(1-33) |
6.7 ± 0.22 |
208 |
3 |
6.7 ± 0.14 |
183 |
3 |
rGLP-1R |
hGLP-2(1-33) |
N.B. |
N.B. |
3 |
N.B. |
N.B. |
3 |