1. Introduction
Intratympanic dexamethasone(ITD) has been reported to be used to treat Méniere’s disease, It is widely used in clinical due to its minor systemic side effects, convenient way of administration which dexamethasone can penetrate directly into the inner ear through the round window membrane and effective treatment effect. However, ITD also has adverse reactions that cannot be ignored, such as transient dizziness and vertigo, pain, tongue numbness, bleeding, tinnitus and persistent perforation. In addition, in our research center, external auditory canal mycosis and tympanic membrane atrophy thinning can be observed in some patients after ITD which has rarely been reported before. Herein, we summarized the characteristics of the particular complications we observed in our research center which preferred to reflect the characteristics of patients in southern China due to their origin.
Since 1985, Fradis M et al. used intratympanic lidocaine (ITL) to treat Méniere’s disease, with an effective rate of over 67.8%[4]. ITL was also widely carried out in our research center. In order to more accurately evaluate the complication characteristics of Méniere’s disease patients treated with ITD, the patients treated with ITL were set as randomized control.