3.5 Laboratory data of COVID-19 patients
Pooled summary of complete blood picture showed leukocytosis (mean =
13.20 x109/L, 95%CI: 10.82-15.59), lymphopenia (mean
= 0.93 x109/L, 95%CI: 0.737-1.125), neutrophilia
(mean = 12.67 x109/L, 95%CI: 8.56-16.76), and anemia
(mean = 10.4 g/dL, 95%CI: 9.55-11.39) in positively confirmed COVID-19
children.
Elevated liver enzyme levels (ALT: mean = 46.86 U/L, 95%CI: 39.1-54.6
and AST: (mean = 52.89 U/L, 95%CI: 45.9-59.8) and hypoalbuminemia (mean
= 27.15 g/L, 95%CI: 23.5-30.7) was reported across studies. There was
marked elevated cardiac markers; troponin (mean = 110.71 ng/L, 95%CI:
59.08-162.3), NT-proBNP (mean = 5,648.78 pg/ml, 95%CI: 3823.17-7474.3),
and LDH (mean = 637.21U/L, 95%CI: 358.7-915.7). Elevated inflammatory
markers were observed; C-reactive protein (mean = 215.58 mg/L, 95%CI:
192.50-238.67), erythrocyte sedimentation rate (mean = 64.64 mm/hr,
95%CI: 54.28-74.99), procalcitonin (mean = 19.24 ng/ml, 95%CI:
8.67-29.80), ferritin (mean = 763.24 ng/ml, 95%CI: 658.86-867.63), and
interleukin-6 (mean = 189.67 pg/ml, 95%CI: 145.48-233.87). there was an
increased evidence for coagulopathy represented as a high blood
concentration of fibrinogen (mean = 6.24 g/L, 95%CI: 4.68-7.80) and
D-dimer (mean = 3.79 μg/ml, 95%CI: 2.57-5.02) (Table 2G).