Statistical analysis
Statistical analyses were performed with SPSS version 25. The two groups
were compared for statistical significance based on Chi Square or Fisher
exact test for categorical variables which are expressed as percentages.
All continuous variables were explored for normality using normality
diagnostics. Student’s t-test was used to analyze continuous variables
that were normally distributed, and the Mann-Whitney U test was used for
variables that had non-normal distributions. Continuous variables were
expressed as means ± standard deviations and/or median with
25th and 75th percentile as
appropriate. Statistical significance was based on a two-tailed P value
of less than 0.05. Details for the repeated measures analysis and linear
regression are provided in the Supplement.